Does Vitrase do more damage to skin and does it dissolve Juvederm evenly? (Photo)

Question

Juvederm and botox 3 weeks ago my face has changed so much under eyes are indentation and dark I'm not happy

Jason Emer, MD · Answer

Vitrase doesn't damage normal skin, it cant due to the pH difference in the medication versus normal skin hyaluronic acid.  I suggest you see a filler expert to assess the area and improve with future treatments.  Best, Dr. Emer.

Ira Vidor, MD · Answer

Hi. Hyaluronidase can be found in two commercially available products- vitrase and hylanex. Vitrase is made from purified ovine (sheep) hyaluronidase whereas hylanex is recombinant. Due to this, hylanex has less incidence of tissue reaction or allergy. Both can be used to dissolve HA fillers. Dissolving filler "evenly" has more to do with injection technique and can not be 100% guaranteed. You can always inject more hyaluronidase or add more filler to even things out. There can be a temporary loss of natural hyaluronic acid in the skin when hyaluronidase is used, but it should not permanently damage it. Best regards, Ira Vidor, M.D.

Does Vitrase do more damage to skin and does it dissolve Juvederm evenly? (Photo)

Answers (2)

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