Belotero is excellent for the fine lines around the mouth, crows feet and even in the forehead. It is not great at filling the deeper nasolabial folds, marionette lines and lips. For those concerns Juvederm is king.As far as comfort of injection, Belotero is injected much closer to the surface and hurts a lot more. In my practice, I will numb the patient to minimize these complaints. Durability - Each person is different and both fillers will last for varying amounts of time from person to person, but Juvederm lasts significantly longer.P.S. There is a new feature on Realself, which is the "Follow" button. It is similar to the "Like" button on Facebook. If you like my response or any of the doctor responses while you research on Realself, you should "Follow" them. You will get email updates, when the doctors you follow post any new answers to questions, post new photos, or have any new reviews.