Can you get a reaction from Belotero one month after injection? (photo)

Question

When I had Belotero injected for the fine lines in my lips, I had initial bruising, and was happy with the results. However, one month later, I developed a swollen lips. One day it was the right side and I used ice to minimize swelling, then 2 days later I woke up with a bigger swollen left side. (See photo) could this happen one month after the procedure?

Joe Gryskiewicz, MD, FACS · Answer

Hi, sorry you are having a problem.  Yes, you can have swelling a month later or even many months later.  This can be serious (granuloma [body reaction to a material or germ], infection, biofilm).  You should return to your doctor as soon as possible for diagnosis.  All the best,"Dr. Joe"

Michael A. Zadeh, MD, FACS · Answer

Hello. I have never seen a reaction like this happen one month after injection of the lips with fillers. You should see whoever did your injections as soon as possible to make sure there is nothing more serious going on. Good luck.

Hratch Karamanoukian, MD, FACS · Answer

Late swelling (> 1 week after injection) and certainly at 1 month after injection of a HA filler is unusual and can be related to granuloma formation or FB reaction or less likely, an infection.Seek immediate guidance from the injecting physician.

Robert M. Freund, MD · Answer

Any filler we inject is a foreign body. These fillers are injected in a sterile manner, so that there is no bacteria in the injection. However, there is bacteria on your skin. The injection can introduce the bacteria from your skin under your skin. Normally, your body fights any small infection with the immune system. However, our immune system does not do a great job of fighting infection that is hiding in a foreign substance, like a filler. If a filler has bacteria on it, this is called a biofilm and is very difficult to eradicate untill the filler disappears.Return to your physician so that this finding can be addressed.Good luck.

Shervin Naderi, MD, FACS · Answer

Hii have never had any patients with this kind of reaction to Belotero, Restylane or Juvederm but it is possible. It is more common with some other fillers like Hydrelle and more common in patients with autoimmune or collagen vascular diseases. See your doctor or injector immediately to possibly have it melted.

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