Belotero Balance is comprised of hyaluronic acid, a commonly found component of our body. The company uses a process called bacterial fermentation to produce hyaluronic acid, and then cross links that to make it more stable. So to answer your question, it is not one of the animal derived HA's, has the same basic ingredient as the other HA's (restylane, juvederm, perlane, voluma), and has a well established track record for safety and efficacy.In my practice I use it primarily in the lower lid/rim area. It's probably the most liquid consistency of the HA's, meaning least likely to form bumps in thin skinned areas like the eyes, or in superficial applications like very fine lines. But for other areas like lips, cheeks, nasolabial, and melolabial folds, I go with other options.