There is no reason to refrain from CoolSculpting simply because you harbor the herpes virus. In the United States, up to 68% of people are infected with HSV-1, which causes cold sores. If you are having an outbreak, and are hoping to treat your submental area with CoolMini, I would just recommend waiting until your skin has cleared. If prior outbreaks are near the treated area, a prescription anti-viral medication should be prescribed before your treatment to prevent activation of the virus. CoolSculpting may be contraindicated in people who have developed shingles from the varicella-zoster virus, which is a type of Herpes. The neuropathy experienced by Shingles sufferers may be re-activated by a CoolSculpting treatment. It is important to have your CoolSculpting done by a board-certified dermatologist, so that pre-existing medical conditions can be identified and problems can be avoided. Please find a board-certified dermatologist who can evaluate you to find out if you are a candidate for this highly effective, noninvasive body-sculpting technique.