DAO Botox: how many units should go into the DAO each side?

For Botox, I mix each 100 unit bottle with 2 ml of saline so each of my injection doses is 2.5 units. I like to start with 2.5 units per side. I get a better result when the Botox is injected at the insertion point of the muscle near the corner of the mouth. If a second injection is required, I place it lower along the border of the mandible. 

Thanks for your question. Prior to any cosmetic treatment with botulinum toxin evaluation of the muscular anatomy should be performed by a trained provider as different facial anatomy require variation in dosing or any area. The majority of patients benefit from 2-5 units of Botox to each DAO which will produce a nice subtle lift to the corners of the mouth as well as can help the appearance minimally of the marionette lines. For maximum benefit I often combine Botox with hyaluronic acids fillers to turn the corners of the mouth and replace the lost volume in the marionette area. 

Thank you for your question.  Botox dosages in the DAOs typically range from 2-4 units per side, to subtly lift the corners of the mouth.  I find that many patients who are interested in Botox injections here can also often benefit from filler injections (with Juvederm or Restylane) to help replace volume loss - this can often provide more dramatic and longer-lasting improvement than Botox alone.  I would recommend seeing a cosmetic dermatologist or plastic surgeon for a formal evaluation.  Best of luck!