Can Botox lead to loss of smell and taste?

No, it is unlikely that Botox caused a loss in smell and taste. If it persists, I recommend following up with your Doctor for a formal evaluation. Best, Dr. Emer

I have never heard of a patient's smell or taste being affected by Botox. I would suggest that you get thoroughly checked out by your physician to rule out any other causes. Best of luck.

I'm sorry to hear that you're noticing these symptoms after your Botox treatment.  The effects of Botox at cosmetic dosages are highly localized, and are typically limited to the individual facial muscles being treated.  To the best of my knowledge, loss of taste and smell have not been reported as side effects in any major Botox clinical trials, and in my personal experience, I've never had a patient who developed these symptoms after Botox.  I would recommend following-up with your plastic surgeon and your primary care doctor to discuss your concerns.  I hope you feel better soon.