Hello mandyo1997. Thank you for your question regarding the bioavailability of subcutaneous injections in the belly after a tummy tuck. After a tummy tuck, the anatomy of your abdominal area can change significantly due to the removal of excess skin, fat, and the tightening of underlying muscles. However, this typically does not drastically alter the absorption of subcutaneous injections, such as insulin or other medications, in the abdominal area. The abdomen remains one of the preferred sites for subcutaneous injections because it has a good layer of fat and is easily accessible. The bioavailability of a medication refers to how well and how quickly it is absorbed into the bloodstream. The subcutaneous fat layer, which lies between the skin and the muscles, is where these injections are typically administered. After a tummy tuck, this layer may be slightly thinner, but it usually still provides an adequate environment for the absorption of most subcutaneous medications. However, it's essential to consider a few factors: Scar Tissue: The formation of scar tissue after surgery could potentially affect absorption. It’s generally advisable to avoid injecting directly into scar tissue because it may be less vascular and could alter the absorption rate. Skin Sensitivity: Post-tummy tuck, the skin in the abdominal area might be more sensitive or prone to irritation, especially in the early months of recovery. You may need to monitor the injection sites for any signs of irritation or inflammation. Consultation with Your Doctor: It’s always a good idea to discuss with your healthcare provider where the best injection sites are for you post-surgery. They might suggest alternative sites, such as the thigh or the back of the arm, depending on your specific situation. In general, the belly can still be used as an injection site after a tummy tuck, but you should consult with your doctor to ensure it’s the best option for your needs. Sincerely, J. Timothy Katzen, MD, FASMBS, FICS