Thank you for your question. To clarify, there are two issues. One is a true allergic reaction to either the tape or adhesive material used before application of the tape. This is a rare condition typically less than 1% of patients have this. More common phenomenon is Blistering that could happen because of swelling and stretching of skin where the tape literally will cause a tear in the upper layer of the skin similar to a burn. This can certainly be avoided by not using tape at all. However, using tape is necessary at times at when I prefer using The new advanced form of tape made by 3M "kind removal silicone tape" which comes off without making a blister.