Does Spironolactone have an initial breakout phase?

Question

I want to start using Spironolactone for my adult hormonal acne but I'm petrified of any initial breakout phase. Does Spironolactone have an initial breakout phase?

Eric Schweiger, MD · Answer

Spironolactone is a great oral treatment for hormonal acne. While it is true that there can be a breakout when its first initiated, there are things that we can do to try to minimize the initial breakout. One option is to simultaneously take oral antibiotics to try and reduce the bacteria on the face and help control the breakouts. Another option is to get cortisone injections initially while we are waiting for the Spironolactone to kick in. Spironolactone is a great option for hormonal acne and most patients feel that the initial breakout is worth the great results they get on the medication.

Davin Lim, MBBS, FACD - Account Suspended · Answer

Yes, it can but the break out phase is much less than Accutane. As suggested, we can have several ways to decrease the break outs-1. Start slow 25 mg , then increase 25 mg every week. 2. Combine with say drospirinone or C. acetate pill3. Use an antibiotic like erythomycin with the Spiro4. If you do have cyst, steroid injections help5. if you have clogged pores or say deep lesions on the chin and jawline area, laser extractions can help. CheersDr Davin Lim Laser DermatologistAcne scar specialistAustralia. Brisbane.

Does Spironolactone have an initial breakout phase?

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