I am a 37 year old female who suffers from hormonal acne and mild rosacea. I have used spironolactone along with Oracea and Acanya gel in the past for my acne and it worked very well. I went off of spironolactone due to a study done years ago on mice/rats where they developed breast and ovarian tumors due to the medication. Is this reason to stop the medication? Is it okay to stay on the medication long term? As I have gone off of the medicine, the acne has completely come back.