Will Botox work for me again if I take a break for one year? What are my alternatives if it continues to not work?

If you have truly developed resistance to Botox and Dysport, then time off from the product will probably not make a difference.  You can try Xeomin which works slightly differently.  If you do not find improvement you can consider overall improvements to skin tone and texture such as Morpheus8, FaceTite,  and lasers.

the treatmetns do not lose effect just because you take time off, I suggest seeing an expert if one stopped working you can consider another.  At home dermarolling should be done between to help prevent and maintain fine line improvement. Best, Dr. Emer.