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In my opinion, the answer to this question depends upon the technique used to deliver the PRP. Many providers utilize micro needling Or a microneedle roller prior to or with the PRP. This technique could be a problem with Accutane usage. If the PRP is injected using the Depo technique, I have not found any difficulties when treating patients on Accutane. In summary, if the skin is intact, PRP and Accutane should not be a problem. Find a PRP expert.
While PRP is excellent for both hair growth and facial complexion and texture, I strongly advise against doing it while on Accutane. You should stop the Accutane 6 months prior to having any procedure. Make sure you inform your surgeon and your dermatologist.