Coolsculpting is best when performed on an area that has an excess number of fat cells. For example, women say, "When I gain weight, it goes straight to my belly." That means that you were born with more fat cells in your abdominal area. It would be great to perform coolsculpting in that area to reduce the number of fat cells there and make that are more proportional with the rest of your body. Then, if you gain weight, it will be more evenly distributed over your body. It won't just "go straight" to one area. The fat loss is permanent after Coolsculpting. You typically lose 20-25% of the fat in the area treated, each time you treat it. I have done it to myself and my staff. It is truly effective and has no down time. Coolsculpting does not affect the menstrual cycle. Best of Luck, Sheila Nazarian