Can eye lid fillers be used to reduce my eye prominence?

Eyelid filler injection can help reduce the prominent eye appearance but they are very limited in what result they can achieve. Surgical option is more definite and substantial but consultation is necessary to determine if you are candidate based on risks and benefits involved.

Undereye and cheek filler will help with your concerns. I don't think based on this single photo that upper eyelid filler is needed. I will defer to the the surgeons on this forum to discuss your surgical options. 

Prominent eyes are a hereditary condition in which the patient is lacking volume in the cheek area. Your face can easily be improved with the use of autologous fat grafting. Find a plastic surgeon near you who can perform this procedure which will provide you with natural and nearly permanent results. Good luck from New York City

It is difficult to assess what you mean by "eye prominence" based on one angle of your photo. Based on your photo, it seems that it's either your right eye is more prominent or the left eye is (ptotic) droopy.   Fillers are not usually indicated to cover "eye prominence" but you can see a physician with expertise in eye evaluation for a good advise how to approach this.

Fillers may help but be sure to consult a licensed injector in your state. You may also want to consider an HA filler with PRP injections. This is also known as a Vampire Facelift

Prominent eye is best treated with surgery. However, the surgery is relatively complex. Fillers can disguise it to some extent if used properly. You need a heavy filler like Juvederm Voluma placed below the orbital ligament pushing the eyelid up. This can significantly reduce the hollowness below the eye and raise the lower eyelid to hide some of the lower scleral show. You  have many plastic surgeons in your area familiar with both surgery and fillers and the intimate knowledge of the anatomy necessary to achieve a good result.