Is hyaluronidase safe? Had overcorrected prejowl sulcus and now looking chinless as it changed my natural face contour.

Hyaluronidase is very safe and rarely causes problems if used properly.  It can lead to subtle atrophy of tissue if used in high doses (which is sometimes necessary), but these changes are not usually permanent.  Small amounts of carefully injected hyaluronidase should be very safe if you truly do not like the results of your filler.  Again, its always best to go slow and dissolve a little at a time, sometimes even doing multiple visits/treatments and dissolving small amounts at a time until the desired result is achieved.

Hyaluronidase is generally quite safe though allergy has been rarely reported to the non-human derived form (Hylenex is the human derived version).  It is more successful with some HA fillers (Restylane) than with others (Voluma) but it always works if enough is injected.  Usually it does not cause indentation just a loss of whatever correction was achieved with the filler, which can always be replaced.  As always it is best to seek a physician who is experienced with these techniques.