Can getting Botox or Dysport while doing allergy shots theoretically increase risk of Botox or Dysport resistance or tolerance?

Question

I’m starting allergy shots soon & also want to start getting Botox or Dysport regularly. I read allergy shots stimulate immune system & cause you to create IgG antibodies. I read Botox triggers antibody formation & in rare cases Botox resistance/tolerance can occur. Since immune system will already be stimulated from allergy shots, theoretically do you think getting Botox while getting allergy shots would cause more Botox antibody production & increase risk of resistance or tolerance to Botox?

Vito C. Quatela, MD · Answer

Very interesting question. Immunotherapy (allergy shots) is a very targeted treatment that drives your immune system to shift its response to specific allergens like ragweed. That is why they test specific allergens in your skin and then target your treatment to those specific allergens. There is definitely some thought that patients can develop antibodies to Botox and thus reduce the effectiveness of the injection. However, I am not aware of any data that would suggest concurrent allergy shots will increase your chances of creating antibodies to Botox or Dysport. Best of luck.

Gary Linkov, MD · Answer

The short answer to your question is probably not. However, there are no studies that have looked at the risk of neurotoxin resistance with simultaneous administration of immunotherapy (allergy shots). Would be an interesting study indeed.I would recommend proceeding with both and not worrying too much.

Gary Linkov, MD
Facial Plastic Surgeon in Manhattan

Anteneh Roba, MD · Answer

I don’t think your allergy shots will affect how effective your Botox injections are. You may want to ask your allergy Doctor just to make sure.

Jason Emer, MD · Answer

Thank you for your question. As long as you do not have an allergy to any of the ingredients in Botox/Dysport, then you will be okay. There is no cross reaction from Botox/Dysport and Allergy shots.  Best, Dr. Emer

Monika Soni, MD · Answer

Thank you for your question. As long as you do not have an allergy to any of the ingredients in Botox/Dysport, then you will be okay. There is no cross reaction from Botox/Dysport and Allergy shots. Best of luck!

Can getting Botox or Dysport while doing allergy shots theoretically increase risk of Botox or Dysport resistance or tolerance?

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Can getting Botox or Dysport while doing allergy shots theoretically increase risk of Botox or Dysport resistance or tolerance?

Answers (10)

Answer: Botox/Xeomin/Dysport Risks/Results--Lasts 3-4 months in new areas of treatment

Answer: Botox/Xeomin/Dysport Risks/Results--Lasts 3-4 months in new areas of treatment

Answer: As long as you do not have an allergy to any of the ingredients in Botox/Dysport

Answer: As long as you do not have an allergy to any of the ingredients in Botox/Dysport

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Everything you need to know about Botox

Our mission is to create a world where every investment in modern beauty is Worth It.