PRP vs PRF for hair loss?

Question

I am seeing doctors offer PRF as a treatment for hair loss and was curious the difference between PRP vs PRF as far as results. Thank you

Alexander Golberg, MD, DO · Answer

PRP (Platelet-Rich Plasma) and PRF (Platelet-Rich Fibrin) are both used for hair loss, but PRF often offers more sustained results. PRF is processed at a lower speed and for a shorter time compared to PRP, which helps preserve more viable cells in the plasma. This results in a gel-like matrix that releases growth factors slowly over time, potentially leading to longer-lasting effects and more effective hair growth stimulation.

E. Jacob Simhaee, MD, FACOG · Answer

Dear patient
Answering to your question both work the same, with PRP you need to use an activator while with PRF you don't need too.

good luck and best of health

Cengizhan Ekizceli, MD · Answer

Both PRP (Platelet Rich Plasma) and PRF (Platelet Rich Fibrin) are natural treatments made from your own blood.They both help reduce hair loss and support new hair growth, but there are some differences between them.
PRP is made by separating the beneficial cells in your blood.After injection, these cells act quickly, but the effect lasts for a shorter period of time.That’s why PRP is usually preferred in the early stages of hair loss.
PRF, on the other hand, is prepared more slowly and contains a natural fibrin network.This network allows growth factors to be released more slowly and over a longer period, giving a longer-lasting effect.For this reason, PRF is often used after hair transplantation or in more advanced stages of hair loss.
Your doctor will determine which treatment is best for you based on your type of hair loss and individual needs.

Jennell Nelson, MD · Answer

The SELPHYL® System is designed for the safe and rapid preparation of Platelet-rich Fibrin Matrix (PRFM) from a smaller sample of blood at the patient point. PRFM contains growth factors and stem cells. It is a more concentrated preparation compared to PRP. It is a also a closed system enhancing sterility.

Anteneh Roba, MD · Answer

I personally haven’t compared the two treatments for hair loss. I prefer PRF for facial rejuvenation and certain musculoskeletal conditions. Theoretically, PRF which is the next generation of PRP should be better since the Growth factors released from the platelets are released over weeks when PRF is used as opposed to PRP which is released and dissipates within hours. The slow release of growth factors seems to be more effective.

PRP vs PRF for hair loss?

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