Is Xeomin the least likely neuromodulator to cause a reaction?

Question

I'm interested in a filler/neuro inj. combo for facial rejuvenation. In 2014, a 100 unit IM inj. of Botox IM for a muscle spasm caused a "panic attack" like reaction 1 hr post procedure which lasted several hrs. An immunologist suggested maybe it was an an anaphylactic reaction. A dermatologist recommended Xeomin as an alternative to based on its formulation. With that and the much smaller dosage used cosmetically, am I a candidate for Xeomin (instead of a similar product)?

Kenneth D. Steinsapir, MD · Answer

As you indicate it was a panic attack rather than mast cell degranulation syndrome leading to anayphylaxis. However, I have an expanded notion of what people experience as clinical botulism.  I have seen individuals experience a generalized panic reaction to larger (and sometimes smaller) doses of Botox.  Xeomin is not an alternative to this.  I suspect if you have a large enough dose of Xeomin or Dysport, you could experience a similar reaction.  You may nor may not experience this with the smaller cosmetic dose.  If you do, I would recommend avoiding any cosmetic botulinum toxin treatments in the future.

Jeffrey S. Rosenthal, MD · Answer

Both Xeomin and Botox are purified proteins used to decrease muscular movement of the upper facial muscles..Botox has been used on the very young and old for a host of problems.  There mode of action is similar so patients can use either.

Glenn Murray, MBBS · Answer

Hi and thank you for your question. As Xeomin is the softest, shortest lasting brand of wrinkle relaxer it can be less likely to cause an adverse reaction such as a ptosis as it is not completely stopping the treated muscle from contracting.
  
Wishing you all the best,
  
Stay absolutely safe and well,
 Dr. Murray from Absolute Cosmetic Medicine

Jason Emer, MD · Answer

Yes, Xeomin or Dysport can be used as an alternative. It will take 1-2 weeks for final results with Xeomin. A combination of fillers, lasers and microneedling/prp can also give improvement. See an expert. Best, Dr. Emer

Edward E. Dickerson, IV, MD · Answer

Thank you for your question. Like all modulators there’s always a possibility of a reaction. However, with Xeomin there’s been little cases of adverse reactions.

Is Xeomin the least likely neuromodulator to cause a reaction?

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Is Xeomin the least likely neuromodulator to cause a reaction?

Answers (6)

Answer: Botox alternatives--Xeomin/Dysport, fillers, lasers, microneedling/prp

Answer: Botox alternatives--Xeomin/Dysport, fillers, lasers, microneedling/prp

Answer: Xeomin and Reactions

Answer: Xeomin and Reactions

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Our mission is to create a world where every investment in modern beauty is Worth It.