Can encapsulated Restylane filler stay in your body forever?

The filler does not last forever. However I have now seen patients with issues related to filler treatments performed more than 8 years ago. These products persist much, much longer than the manufactures first informed physicians regarding the persistence of the hyaluronic acid fillers. Just like the fact that the placement of product requires a high level of skill, its removal also requires skill. Occasionally I do see an individual who it certain that they had a hyaluronic acid filler but it turns out (on biopsy) that they actually had a different type of filler.

Keep in mind, it takes a series of treatments to fully dissolve filler and it's difficult to determine how many treatments you would need. However, it should not cause problems long-term. Best, Dr. Emer

Keep in mind, it takes a series of treatments to fully dissolve filler and it's difficult to determine how many treatments you would need. However, it should not cause problems long-term. 

It is possible this occurs and is related to collagen reaction to the filler. There is no side effects from it staying there. Surgery would easily remove it. Hyaluronidase should have no negative effects on the skin.