Does Botox effect egg quality?

Question

I'm about to start IVF (3 month egg collection) and wondered if botox would be a problem. Does it get into the blood stream and could it potentially damage the eggs? Egg transfer isn't due until May.

Sonia Badreshia-Bansal, MD · Answer

Thank you for your question. I would recommend not doing Botox treatment if you're trying to get pregnant.  I hope this helps!

Jerome Edelstein, MD · Answer

There is no evidence suggesting that Botox would affect egg quality in any way, but just to be on the safe side, you should refrain from having Botox treatments performed when pregnant.

Deborah Kessler Hudak, MD, MHA · Answer

Botox acts at the neuromuscular junction, blocking the chemicals at the end of a nerve from getting into their receptor site in a muscle.  In this way, it prevents muscle contraction.  It it gets into the blood stream, because it was inadvertently injected into a blood vessel, it could cause untoward side effects.  This is a very rare occurrence, and generally only causes problems when the amount of injected Botox is great, too. When injecting, we are targeting injections into specific muscles, (NOT vessels), and use an "aspirate first, then inject" technique to be sure not to inject into a vessel.   I have never heard of it affecting egg quality or pregnancy---however, it is common practice here in the USA to avoid administering any medications to pregnant females unless it is absolutely necessary.Debbie Kessler Hudak, MD

Dominic Castellano, MD - Account Suspended · Answer

Thanks for the question.  It is generally recommended that women who are pregnant refrain from continuing their Botox treatments.  There are no known side effects, and you may continue with Botox during IVF.

F. Victor Rueckl, MD (in memoriam) · Answer

There are many people who receive Botox and go through IVF. It's not recommended to have Botox once you are pregnant (though there is no research done to say anything happens to the developing fetus we just don't do elective procedures on pregnant women). But you can actually see on this site that many people become pregnant right after receiving a Botox treatment - intentionally or otherwise - so the eggs remain the same. "This answer has been solicited without seeing this patient and
cannot be held as true medical advice, but only opinion. Seek in-person
treatment with a trained medical professional for appropriate care."

Does Botox effect egg quality?

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