Can Kybella be used in lips? (Photo)

Question

Can kybella be used in lips the remove fat lumps from fat grafting 2 years ago. Dr removed some but not all. My have one internal lip scar too. Not sure. What are the positives or negatives to think about? Thanks.

Dallas Buchanan, MD · Answer

Thank you for your pictures and questions. The bottom line is that there is no really good clinical information out there about this usage because there is no FDA indication for Kybella in any area other than the submental area. That being said, myself and many other providers have had good success with Kybella in "off-label" uses in other areas of the body. There are really no clinical indications to use it in the lips, but if you have had fat injected into the lips that you want gone, I think it would be a reasonable thing to attempt. I would say the worst case scenario is that it does not help much if the fat is encapsulated. 
Hope this helps!

Dallas Buchanan, MD
VIVIFY plastic surgery
Tampa, FL

Jason Emer, MD · Answer

You need a full assessment. Consult with a facial sculpting expert to discuss your best next steps. -Dr. Emer

Darryl J. Blinski, MD · Answer

It is off label use. So I might hyper dilute the KyBella and use micro droplets in multiple sessions startig with 1 lump only. Expect fees in $5,000 ranges.

Mats Hagstrom, MD (license on probation) · Answer

Direct surgical excision is probably the most effective way of removing the previously grafted fat in the lips.

Kybella it’s not FDA for anything other than under the chin. When the chemical starts dissolving fat cells it also does this on the myelin sheath which is a fatty covering necessary for nerve function. The inflammatory response from this treatment is pretty dramatic and lips tend to swell quite a bit because they’re so vascular.

I don’t think you’re gonna find anyone who has experience and simply finding any provider who has ever done this before is going to be challenging.

I personally would not mate if I was going to attempt it I would go very conservatively with a test dose to see if the patient tolerated it and then increase the concentration or the amount injected.

This is a conservative and safer approach but causes the patient to have to undergo several rounds of lip swelling.

All patients and providers need to ask themselves how can the fat be removed if their results are not to their liking before injecting fat in any part of the body.

Facial fat transfer is by its inherent nature unpredictable, imprecise and crude in relationship to word fillers can do.  I realize that for you the decision was already made but others considering facial fat transfer should take note of how complicated this can turn out.

Best,

Mats Hagstrom MD

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