Can the swelling of C02 fractional laser cause the ability to barely smile?

Co2 laser doesn't effect your ability to smile but botox injections above the lips if improperly placed or too high a dose in the wrong area can.  It takes 10-14 days for the botox to be fully active that is why you are noticing it now.  I suggest you speak to your physician.  It will be 3-4 months before this improves.  Best, Dr. Emer.

Thank you for your question.  Swelling is to be expected following CO2 laser resurfacing, especially when the treatment is a more aggressive one which would be done for deeper lines/wrinkles.  If you are having a problem with your recovery, contact your physician who performed the treatment immediately.  You should be examined to make sure you are not suffering a complication.