Thanks for the question.
Juvederm can indeed be used to manage the deep wrinkles in the glabellar region. I would initially treat the area with a chemodenervation product such as Botox Cosmetic or Dyport, weakening the muscle groups and minimizing the wrinkle. Once this is accomplished, the injectable filler (Juvederm) can be used to manage any residual stigmata of wrinkling in this area. Additionally, the use of Botox in combination with the filler will prolong the effects of the filler.
Glenn Vallecillos, MD, FACS