Is It Ok to Increase my Accutane Dosage from 20mg to 40mg Daily?

This is my third dose of accutane since 2007 - i took 20mg daily from Dec 2007 to Jun 2009, and then 20mg from Oct 2010 to Apr 2011, 30mg in May to June 2011 and then returned to 20mg till Oct 2011. I started my third dose of accutane in Aug 2013 (20mg daily) and I'm still getting pimples. Is it ok for me to increase my daily dose to 40mg? I'm 32, female, and I weigh 106bs.

Doctor Answers 1

Accutane dosing

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Accutane dosing is highly provider dependent.  The general recommended dosing regimen is 1-2 mg/kg/day with a total dose in the range of 120 - 150 mg/kg per round of treatment.  For a 106 lb person that would equal 48 kg, so a 40 mg per day dose would be just fine, or even a tad under-dosed.  However, the most important part of the equation is the total dose, so as long as you get over 5700mg of the medication, you will be fine.

Sugar Land Dermatologist

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