Is It Ok to Increase my Accutane Dosage from 20mg to 40mg Daily?

Accutane is a go-to medication for patients with recalcitrant cystic acne. It can reduce pore size and also reduce sebum production in your skin, making it less oily; and in turn, dryer. Accutane can be used to control acne, but patients receiving the medication should be carefully monitored. In terms of skincare, always wear an appropriate sunscreen and reduce direct sun exposure. In my patients, I recommend a good ceramide moisturizer such as Elevase whenever they are on Accutane. This will keep the skin hydrated and reduce the oiliness of the skin that is associated with oil-based moisturizers.

Best,
Dr. Karamanoukian
Realself100 Surgeon

Accutane dosing is highly provider dependent.  The general recommended dosing regimen is 1-2 mg/kg/day with a total dose in the range of 120 - 150 mg/kg per round of treatment.  For a 106 lb person that would equal 48 kg, so a 40 mg per day dose would be just fine, or even a tad under-dosed.  However, the most important part of the equation is the total dose, so as long as you get over 5700mg of the medication, you will be fine.