I'm 5'3, weight 110, bra size small B cup. Can I realistically achieve the look and size of Kate Upton? (Photo)

Only Kate Upton is Kate Upton.  You might get close but only Kate Upton is Kate Upton.  You are you.  You have to work with what you have and you did not provide even a picture for comparison.  Because of that, it is impossible to tell you much.  I would suggest that you schedule an appointment with a board-certified plastic surgeon who can examine you in person, discuss your goals, and review your options.

It is very possible to achieve that look and be full and natural at the same time. Surgical technique and implant selection are key to this. The exact choice of size that will work best for you is an important decision that you should make with your board certified plastic surgeon. 3D Vectra imaging and simulation, the Mentor gel sizing system, rice filled implants at home in your bra, and bio-dimensional analysis are all methods that can be employed to help you come to a decision. Because size is such an important component of decision making in breast augmentation our office employs all of these techniques with each patient to ensure the highest rate of satisfaction possible. Good luck with your decision!

Kate Upton is a supermodel so using her for your goal breasts is probably unrealistic.  That does not mean you can't achieve an excellent result based on YOUR preoperative breast shape and size, chest measurements, skin elasticity and desired size.  I would recommend having some flexibility in your desire for a DD-cup as this may be hard to achieve at your height of 5'3" without making you look like you have gained weight.  A full D-cup breast will be ample on someone with your somewhat smaller frame.  Also, consider using shaped implants or high profile implants to achieve a larger breast size that does not appear too wide.Rather than trying for a specific cup size, work with a board certified plastic surgeon to achieve your goal of very large, full, youthful breast with a natural appearance.  It will look great on YOU which is what really matters.  If they happen to also look like Kate Upton's breasts, all the better!

Thanks for your question.  When my patients come in for breast augmentation, my nurse works with them as they try on the different sized implants which allows them to see what size they like best on their bodies. I help guide them to a shape or style implant - round or shaped, moderate or high profile - that works for their body type.  I suggest making a consultation with a board certified plastic surgeon to determine what will work best for you.

Can not answer without your forgotten self breast photo posted! Maybe seek in person opinions....///////.

Thank you for the question. Unfortunately, online consultants will not be able to provide you with specific enough advice (regarding specific breast implant size/profile) to be truly helpful.  Generally speaking, the best online advice I can give to ladies who are considering breast augmentation surgery (regarding breast implant size/profile selection) is:
1. Concentrate on choosing your plastic surgeon carefully.  Concentrate on appropriate training, certification, and the ability of the plastic surgeon to achieve the results you are looking for. Ask to see lots of examples of his/her work.
2. Have a full discussion and communication regarding your desired goals  with your plastic surgeon. This communication will be critical in determining  breast implant size/type/profile will most likely help achieve your goals. 
In my practice, the use of photographs of “goal” pictures (and breasts that are too big or too small) is very helpful. In bra sizers can be useful communication tools also. I have found that the use of words such as  “natural and larger looking” or "DD cup" etc means different things to different people and therefore prove unhelpful.
 Also, as you know, cup size varies depending on who makes the bra; therefore, discussing desired cup  size may also be inaccurate.  The use of computer imaging may be very helpful during the communication process.
3.  Once you feel you have communicated your goals clearly,  allow your plastic surgeon to use his/her years of experience/judgment to choose the breast implant size/profile that will best meet your goals.  Again, in my practice, this decision is usually made during surgery ( after the use of temporary intraoperative sizers).
I hope this, and the attached link (dedicated to breast augmentation surgery concerns), helps. Best wishes for an outcome that you will be very pleased with.