The best treatment for addressing concerns at the corners of the mouth depends on the specific issue you are experiencing, such as sagging, lines, or volume loss. Here are some common treatments: Dermal Fillers: Hyaluronic acid fillers can be used to add volume and lift the corners of the mouth, reducing the appearance of marionette lines and creating a more youthful, uplifted appearance. Botox: Botulinum toxin can relax the muscles that pull down the corners of the mouth, helping to create a more neutral or slightly upturned appearance. Laser Resurfacing: This can improve skin texture and reduce fine lines around the mouth by stimulating collagen production. Chemical Peels: These can also help improve skin texture and tone, addressing superficial lines and discoloration. Thread Lifts: This minimally invasive procedure uses dissolvable threads to lift and support the skin around the mouth. Skincare Products: Topical treatments like retinoids and peptides can improve skin quality over time and may help in maintaining results from other procedures. It's important to consult with a qualified dermatologist or aesthetic practitioner who can assess your individual needs and recommend the most appropriate treatment plan. They can provide guidance based on your skin type, the severity of your concerns, and your desired outcomes.