350cc to 255cc - are peptides safe to use post breast implant revision surgery?

Your question is very thoughtful, and it’s great that you’re approaching healing with such awareness. Peptides like BPC-157, TB-500, and GHK-Cu have gained popularity for their regenerative and anti-inflammatory properties, but their use in the context of breast implant surgery should be approached cautiously.
Here’s a breakdown of considerations:
BPC-157 and TB-500: Both are known to promote tissue repair, angiogenesis, and inflammation control. While they may aid wound healing, their effect on fibrotic capsule formation around implants is not fully understood. Theoretically, accelerated healing could encourage faster or firmer capsule formation, which might interfere with proper implant settling—especially important as you’re reducing size and want smooth pocket adaptation.
GHK-Cu: Often used for skin regeneration and collagen support. It’s less associated with deep fibrotic activity and may be safer in terms of promoting balanced healing.
That said:
No current clinical studies definitively confirm whether these peptides help or hinder implant pocket behavior, and most evidence is anecdotal or from animal models.
Since you previously experienced premature capsule stabilization on the right side, minimizing anything that might accelerate capsule formation too early seems reasonable.
In most cases, the capsule starts forming within the first few weeks post-op. The first 6 weeks are especially critical for implant positioning and tissue adaptation.
If you’re considering peptides, it may be safer to:
Delay their use until after the initial 4–6 weeks, when implant positioning is more stable
Discuss your plan with both your surgeon and a knowledgeable medical provider experienced in peptide therapy
I hope this gives you a balanced overview. Your cautious approach is wise, and personalized guidance from your surgical team will be essential.
— Güray Yeşiladalı, MD

Hello,
Thank you for your question and for providing helpful surgical context. BPC-157, TB-500, and GHK-Cu are peptides commonly used for their regenerative and anti-inflammatory properties, and while animal data and anecdotal reports suggest they may accelerate soft tissue healing, there is currently no robust clinical data on their effects in the setting of breast implant surgery—particularly regarding capsule formation or implant settling. Theoretically, accelerated healing could potentially contribute to premature capsular contraction or limit pocket expansion, especially in the early postoperative phase when implant mobility is essential. Given your history of asymmetrical settling and revision, it may be prudent to delay or avoid systemic peptide use until your surgeon confirms that implant position is stable. Downsizing from 350cc to 255cc may also influence pocket dynamics, so careful post-op monitoring and massage (if recommended) will be key. Always consult your plastic surgeon before using any adjunct therapies, as they can tailor guidance based on your surgical technique, implant type, and tissue characteristics.

I would strongly advise against using any peptide or non studied products for at least 8-12 weeks after surgery. These products likely will have little or no effect, but because they are unstudied and not regulated- steering away from them until the capsule has established is best.... Follow the advise of your surgeon for your best results.
OPS

Peptides have been increasingly popular lately in various fields in medicine. When it comes to plastic surgery and implants, not much research has been done to determine if it is safe and effective, and if it has any effect on capsule formation. Additionally, this decision should be discussed with your plastic surgeon to see if it is an option for you.

Although this has not been tested, it seems unlikely that the peptides you are using would cause any issues with you implant surgery, and might help.

Dear Tluna,
I understand your concern. It is best that you consult your plastic surgeon regarding post operative care and management (i.e including massage techniques and timing) specific to your case. Your surgeon knows your condition well and has preferences on when and what to use for faster healing and recovery. Post operative care and management depends on the type of surgery performed and the technique used during surgery among other factors.It is best, however, that you follow your plastic surgeon's advice on post operative care management for a smooth and faster healing and recovery.
Daniel Barrett, MDCertified, American Board of Plastic SurgeryMember, American Society of Plastic SurgeryMember, American Society of Aesthetic Plastic Surgery

This question is best answered by your surgeon as opinions vary. She/He is most familiar with your medical history and your planned surgery. Your surgeon will advise which medications, including supplements and over the counter medications are okay to continue and which to stop.

Your surgeon is the one you need to ask this question. If in doubt, hold off taking them since things to increase bleeding may be present. Extra protein will not make "healing too fast" nor cause capsule formation.

Hello, I am Doctor Sealtiel, I am reading about peptides, therefore I would not dare to use it because it has been prohibited since 2022, by an association as serious as the FDA, there are other cares to achieve optimal results in your surgery to achieve optimal recovery, remember that reaching healthy surgery, making healthy habits such as having a diet and practicing regular exercise that also contributes to having excellent results I hope I have helped you