What is the difference between compound semaglutide vs ozempic?

If the compounding pharmacy uses semaglutide base, which they are supposed to, it is essentially the same as ozempic. I've prescribed compounded versions to hundreds of patients with no issues.

Hello and thank you for your question! Ozempic is the FDA-approved brand-name version of semaglutide, made by Novo Nordisk with strict quality control.

Compounded semaglutide is not FDA-approved, but it can be very safe when made by a reputable compounding pharmacy. The key is that your provider does their research—using only trusted, accredited pharmacies that follow high-quality standards.

Should you worry?
Not if you're under the care of a knowledgeable provider who ensures the compound is the correct form (semaglutide base, not salt) and comes from a certified pharmacy. When done right, many people use compounded semaglutide safely and effectively.

If you’re 25 lbs overweight, you may qualify for Wegovy (FDA-approved for weight loss), but compounded versions can be a good alternative when prescribed responsibly.

Best of luck!
Genie Alexander, RN BSN
for Anna Petropoulos, MD FRCS
Center for Classic Beauty
Boston & Danvers, MA

Ozempic is a brand name for the GLP-1 medication semaglutide. Compounded semaglutide would have the same side effects as Ozempic,. Patients are often able to obtain the compounded formula for far less than the brand name Ozempic.