Ozempic and pancreatitis

Question

I have been seeing various news reports linking Ozempic to pancreatitis, which could then ultimately lead to pancreatic cancer- perhaps the most deadly cancer of all. I’m wondering what thoughts people have on this and if they have seen data to support or negate it?

Jerimiah Mason, MD · Answer

The risk of pancreatitis is extremely low, and is more likely due to gallstones from rapid weight loss.  I have yet to see a patient develop pancreatitis from a GLP-1 agonist in my practice, and I've treated hundreds of patients.

Brandon Richland, MD · Answer

Hello, and thank you for your question. Yes, Ozempic can increase one’s risk for pancreatitis, but it can also be caused due to alcohol abuse, previous occurrences of pancreatitis, and gallbladder stones. Recurrent episodes of pancreatitis can possibly lead to pancreatic cancer. If pancreatitis would occur with Ozempic, the patient would need to stop the medication. I would recommend consulting with a healthcare professional to discuss your concerns and to see if you are a good candidate for Ozempic.

Anna Chacon, MD, FAAD · Answer

Ozempic works by binding to GLP-1 receptors and stimulates insulin release from the pancreas when you need it. It helps to lower your blood sugar levels and A1C. It also helps to reduce the amount of sugar released by your liver and slows down food leaving your stomach to help prevent blood sugar spikes. Ozempic may raise your risk for pancreatitis. To help prevent these health problems, avoid excessive alcohol use during your Ozempic treatment and foods to avoid Ozempic side effects. Foods that are high in fat, sugary foods and drinks, ultra-processed carbohydrates, and starchy vegetables. Hope this helps.

Camille Cash, MD · Answer

While Ozempic has not been proven to cause pancreatitis, there is a rare risk of inflammation of the pancreas in those who use Ozempic.  There are risks and benefits to every medication.  It is important that your physician evaluates if you are a good candidate for the medication.  You can determine if the risks are worth the benefits.

Sharon Y. Giese, MD · Answer

Pancreatitis is a rare complication of taking GLP-1 agonists, such as Ozempic. Pancreatic cancer is not an adverse event from taking this medication. It is important to stay hydrated while on this medication.

Howard Pyo, DO · Answer

As a medical professional, I can inform you that while there have been complaints relating pancreatitis and Ozempic (semaglutide), the evidence is inconclusive. Although the exact correlation between Ozempic and pancreatic cancer has not been conclusively demonstrated, pancreatic cancer is a grave issue. It's critical to share any worries you may have with your healthcare provider so they can offer tailored guidance based on your medical background and the most recent findings.

Erika Sato, MD, FACS · Answer

With Semiglutide treatment (Ozempic), you are followed by a physician. Lab tests are drawn intermittently. If your prescribing doctor is not your PCP, you are also to have a yearly visit with them. Side effects or complications are therefore caught early and the medication will be stopped and any complications sent for appropriate treatment.

Edgar Serrano, MD - Account Suspended · Answer

While there have been concerns raised about a potential link between Ozempic (semaglutide) and pancreatitis, it's crucial to rely on scientific studies and official health organizations for accurate information. Consult with your healthcare provider who can assess your individual health profile, discuss potential risks, and guide you based on the latest research and regulatory updates related to Ozempic. It's important not to make decisions solely based on news reports but to consider information from reputable medical sources.

Ozempic and pancreatitis

Answers (8)

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