Facial asymmetry is very common, and it can become more noticeable with aging as the soft tissues lose volume and descend at different rates on each side of the face. For a full facial rejuvenation, I would first recommend a detailed facial assessment to identify whether the asymmetry is mainly caused by bone structure, volume differences or soft-tissue descent. Depending on your anatomy, a combination of a facelift, midface rejuvenation and conservative fat grafting may help improve overall facial balance and restore a more refreshed appearance. However, it is important to understand that surgery can improve asymmetry but may not create perfect symmetry. The best treatment plan should be tailored individually after a proper examination and evaluation of your facial structure.