Can Botox effectively reduce/shrink submandibular glands?

Dear Clovered,If performed correctly and consistently yes Botox can reduce submandibular gland size. This is because Botox injection will reduce the function of the gland, which over time will cause it to decrease in size. Please note that I would not recommend Botox injection into this area as it could carry unwanted side effects, especially injecting at the depth needed to affect the gland.Good luck,Nirmal R. Nathan, M.D.

Certified, American Board of Plastic Surgery
Member, American Society of Plastic Surgeons
Fellowship-trained Craniofacial Surgeon

Hi,This is a great question. In theory, botox can reduce the salivary gland output which some people believe will result in shrinkage of the gland. In practice, this end result is elusive. The protocol many use is 20U per gland over multiple treatments. Best,