Does finasteride ever just stop working or slowly lose effectiveness?

Question

I've been on finasteride for 5 years now and started at nw5 brought me back to nw3 vertex. I take it everyday single day. I've never missed a single dose. I have 2 questions for you. 1.Does finasteride ever just stop working or mainly slowly lose effectiveness but continue to slow my hair loss? 2. If I switch to dutasteride how quickly would take for dutasteride to stop my hair loss once I transfer off finasteride? I don't want to get off fin and lose ground while I begin dutasteride. You know?

Marco Barusco, MD · Answer

Hello,

Thank you for your questions! Finasteride doesn’t suddenly stop working, but over time, its effectiveness may gradually reduce as hair loss progresses naturally with age. That said, it typically continues to slow hair loss, helping you maintain more hair than you would have without it.

Switching to dutasteride is a great option if you’re looking to enhance your results. It’s a more potent DHT blocker, and transitioning directly from finasteride ensures you maintain consistent hair loss control without any setbacks. Be sure to discuss the switch with your doctor to tailor the approach to your needs.

Best regards,
Dr. Marco Barusco

Gokay Bilgin, MD · Answer

While finasteride can be effective for many individuals, it's important to note that individual responses to the medication may vary. Some people may experience a gradual decline in effectiveness over time, while others may find that the medication continues to slow down their hair loss for an extended period.
In certain cases, finasteride may not work as effectively or may appear to stop working altogether. In this case you can switch to dutasteride without losing your hair.

Sujeev Bains, MD · Answer

Hello,AGA is multifactorial so DHT blockers may require other treatments modalities to eventually slow hair lossOnce finasteride is discontinued it takes a few weeks for DHT to increase which allows for a switch to dutasteride without losing effectiveness

Audrey G. Bauer, MD · Answer

Finasteride is effective in about 95% of patients.  It takes a bit of time to see the effects as you may have noticed (no less than 6-12 months) and then the effect "peaks" around 24 month and stabilizes.  Finasteride does NOT regrow lost follicles although you may have felt like it did for you.  Instead what it does is a) keeps hair in the growth phase longer and b) encourages hair follicles that have miniaturized to cycle back toward thicker, more substantial "terminal" hairs.  This second effect is why people think they regrew hair.  In fact, those follicles were still there, they were just producing very small, pale hairs and when those hairs became more substantial and noticeable we think they are "new" .  So at this point, the finasteride is probably still working perfectly fine but is just at it's peak effect and will keep your hair in it's current state for the foreseeable future, which is frankly, what we expect and the best result we can ask for.  Any further "improvement" would need to be via FUE/FUT transplant most likely.  
On occasion, I see a patient for whom finasteride loses it's effectiveness after 15-20 years and sometimes switching them to dutasteride helps resolve this issue.  But in those cases, it's an obvious re-initiation of hair LOSS.  I hope this answers your question.

Does finasteride ever just stop working or slowly lose effectiveness?

Answers (4)

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