Thank you for your question. Creases in this area are commonly related to muscle activity. The muscle contacts and creates a crease that over time can get deeper and deeper. The use of neuromodulators such as botox, dysport or xeomin can prevent the muscular activity and prevent the formation of creases and soften creases that are already present.At times, the creases have been present for such a long time that simply preventing muscle activity does not give you the result you are looking for. It's like when you fold a piece of paper over and over and then try to iron it - it doesn't always remove the crease. For these situations, filler can be considered. It is important to realize that any opinion given here does not replace the value of a face-to-face consultation. An evaluation without examining you, physically feeling the tissue, assessing your desired outcome, taking a full medical history, and discussing the pros and cons of the proposed procedure with you may not be in your best interest. I would recommend you find a facial plastic surgeon in your area that you trust and feel comfortable with to discuss your concerns. Good luck! Marcelo Antunes MD