Would 500cc high profile be enough to go from a B cup to an E cup?

Thank you for sharing your question and best wishes on your breast augmentation.  Breast implant sizing is an inexact science, relative to a woman's bra measurement, as there is no direct correlation between cc size and bra cup.  In general taller, wider women will require a large implant cc size then a more narrow, shorter patient.  It sounds as if it may be wise for you to "try on" several of the implants so that you can have a better visual representation as to what they would look like. The exact size will be unknown, but remember that it is better to fit your bras to your breasts rather than the other way around.  Hope this helps

Depending on the individual anatomy and desired results, estimations and measurements should be made for each patient individually along. The elements that form up the breast shape and size and the overall frame can be different in each person. It is best to consult a board certified plastic surgeon who is experienced in cosmetic breast surgery in person and discuss your goals and options after a physical examination.Hope this helps,Ali Rıza Öreroğlu, MD FEBOPRASEuropean and Turkish Board Certified Aesthetic, Plastic and Reconstructive SurgeonIstanbul, Turkey

After I measure and discuss goals with my patients, we then look at pictures of women with similar measurements with different size breast implants. My patients tell me that this process is very helpful in determining what size breast implant is right for them. 
Dr. Ted Eisenberg, Board Certified Plastic Surgeon and Author

Cup sizes are not standard across bra makers, and implant sizing is NOT based on height, weight, BMI, or desired cup size.  This is something you will need to do IN PERSON with an experienced surgeon to determine what works well for you, and to get advice about if what you like is possible and what to expect with regards to results.  Be sure to discuss your goals and concerns with your board certified plastic surgeon and consider the pros and the cons. Be certain your surgeon is properly certified.  I've attached a link where you can start your search.  

hello thank you for your question and provided information as well.. based in your question its difficult evaluate you if the case dont have a picture, my recommendation is get  a consultation in person with a plastic surgeon to discuss all about theme.

At size 32 B, each
100 cc of implant corresponds to 1 cup size change.  300 cc implants would take you up to size 32
E.  I do not recommend 500 cc implants
since they weigh over 1 lb each, will likely descend and result in complications.  Implants are not lifetime devices and half
are removed at 9.5 years.  An alternative
to consider instead of implants is fat transfer.  Best Wishes,Gary Horndeski, M.D.