How Do I Get Rid of Wrinkle Filler if I Don't Like the Results?

The effects of injectable fillers that are composed of hyaluronic acid, such as Juvederm, Restylane and Teosyal, can be reversed with an injection of hyaluronidase. Hyaluronidase dissolves hyaluronic acid. Permanent fillers that are composed of other materials can be removed surgically.

You are able to dissolve the product with Hyaluronidase if a hyaluronic acid dermal filler was used like Restylane or Juvederm. Best of luck, Dr. Nima!

Hyaluronic Acid based fillers like Voluma, Restylane can be reversed with Hyaluronidase, which is injected into the area that was treated with a filler. The more permanent fillers like collagen will have to be removed surgically.

Undesired results after hyaluronic acid based dermal fiiller injections can be managed in the following way:
1. Wait as the product is reversible so will dissipate and disappear over time.
2. Hyaluronidase injections - this enzyme breaks down hyaluronic acid within 24-48hrs
3. Touch up the results with further injections to improve the result. 
Hope this helps!
Dr Rupert 

The vast majority of patients who
undergo treatment with injectable fillers are extremely happy with their
results.Unfortunately, we occasionally
see patients who aren’t happy and want their procedure reversed.When
this situation arises, the ability to reverse the process is entirely dependent
upon the injectable filler used.Hyaluronic acid fillers can be easily reversed with the enzyme
hyaluronidase.Fillers in this category
include Juvederm, Perlane and Restylane.Artefill,
Sculptra and Radiesse are fillers that don’t contain hyaluronic acid.When patients are unhappy following the use
of these agents reversal can be difficult.Since hyaluronidase doesn’t work in this situation extraction of the
material is the only viable option.Unfortunately this procedure doesn’t always work and can be difficult to
perform.When
patients are unhappy with the results of injectable fillers they should consult
their surgeon.In some cases, the
process can be reversed by using hyaluronidase or mechanical extraction.

Most patients find the immediate results of soft tissue filler treatments very satisfying. If an undesirable result occurs, your treatment provider should be able to discuss and carry out all of the treatment options.

Removing the effects of a "filler" treatment can be difficult. This is why any filler treatment needs to be done carefully, conservatively and only by very experienced and Board Certified Specialists. Hyaluronic Acid based dermal fillers have the additional safety of being partially or completely reversed with time or with the injection of a commercially available enzyme known as Hyaluronidase.

Even in very experienced hands, any filler treatment could result in unwanted results or a complication. The management of these undesirable results should be discussed before you have a treatment. Other techniques for reducing unwanted results are occasionally needed and are known to experienced and qualified specialists.

Dr. Mosher

The key is to choose a reputable, experienced board-certified aesthetic physicians for your facial filler injection. Vast majority of the time, in the right hands, aesthetic filler injections are instantly gratifying and do not require reversal. For first timers, it may be desirable to utilize hyaluronic acid fillers such as Restylane or Juvederm, so that in the very unlikely scenario that you are not happy with the cosmetic outcome of the filler injection, there may be an option for complete reversal with hyaluronidase.

The beauty about hyaluronic acid fillers is that they are reversible via injection of an enzyme known as hyaluronidase. However, in my hands, the need for use of this reversing agent has been very rare. In general, satisfaction from fillers is very high with two exceptions: too little injected or too much injected. The one anatomic area to be very careful with is injection around the eyes. The filler to be used, if at all, is a hyaluronic acid filler (Juvederm, Restylane). Radiesse, which is made from calcium hydroxylapatite is a fantastic filler in the nasolabial folds, but not recommended around the eyes.

Nonsurgical rejuvenation of the eyes, cheeks, lower face and neck have become very popular in-office procedures in the past few years. Hyaluronic acid-containing injectable agents, such as Restylane, Perlane, Juvederm Ultra and Juvederm Ultra Plus are now used routinely not only for filling, but for volumizing, shaping and contouring of the eyebrows, the region under the eyes, smile lines, "marionette" lines and jowls. These procedures take only minutes to perform and often engender a "Wow!" reaction when patients look in the mirror immediately after treatment.

On rare occasions, particularly around the eyes, where the skin is especially thin (even in youth) and around the mouth, due to the anatomy of that area, small bumps or other irregularities may occur following the injection of any of these materials.

In these uncommon instances, enter the cavalry: hyaluronidase. Hyaluronidase is an enzyme that dissolves hyaluronic acid. Injected in minute droplet quantities, the hyaluronic acid fillers and volumizers can usually be dissolved away completely in one to three days. The enzyme seems to preferentially melt the injected hyaluronic acid rather than the native variety. All this makes a great "safety valve," and I routinely inform patients who are anxious first timers to fillers and volumizers that we have this treatment available "just in case" they feel they need it, which fortunately seldom occurs. The fact is that I store it in my office fridge just to reassure patients and have seldom ever have needed to use it.

Hyaluronidase is a naturally occuring enzyme produced by bacteria that digest the hyaluronic acid normally present in the skin., It can also be used to digest the hyaluronic fillers (Restylane, Prevelle Silk, Hyalform, Perlane, etc) that are injected into the skin.