Botox resistance: A return of clinical response after complete secondary treatment failure?

Question

For the doctors who have experienced patients with true BoNT/a resistance, that is, complete secondary treatment failure across all brands. Have any of your patients ever responded again after a long treatment break? If so, please advise how long? Studies show anywhere between 3-10 years however there isn’t much confirmation of a return to clinical responsiveness even when antibodies have dropped into the negative range.

Camille Cash, MD · Answer

You may want to consider Daxxify.  It is a new neuromodulator on the market that is different from Botox.  Daxxify results can last twice as long as Botox- or even longer!  See a provider near you to learn more.

Jason Emer, MD · Answer

If Botox is not an option for you, Dysport or Xeomin are the next options. I suggest dermarolling at home to give the skin Botox-like effects with at-home treatment. See an expert. Best, Dr. Emer

Leonard Grossman, MD · Answer

Botox and similar product resistance is not that uncommon. Patients who are resistant to type a botulism toxin respond well to botulinum toxin type B, namely Myobloc. Myobloc works well with exactly the same results except it starts to work almost immediately but the results also do not persist as long as those with Botox and similar. I have been using Myobloc for the last 27 years with a great deal of success. I hope this helps and good luck from New York City Plastic Surgery.

Botox resistance: A return of clinical response after complete secondary treatment failure?

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Botox resistance: A return of clinical response after complete secondary treatment failure?

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Everything you need to know about Botox

Our mission is to create a world where every investment in modern beauty is Worth It.