Can I have Botox if I'm on Xolaire (omalizumab)?

Thank you for your question brightsideoflife. Botox is a purified protein used to address wrinkles associated with
facial expression. Certain medications such as aminoglycoside antibiotics may potentiate the effects of Botox. Biologic medications are not known to interfere with Botox. If I had a patient on Xolaire who desired Botox I would tell her that it should be fine. Please consult with a doctor for specific recommendations. Good luck!

There should not be any interaction between Botox and Xolaire. However, if you are concerned, you may want to try a "test" and have your surgeon inject some Botox into your arm. Hope this helps --

Hi There Thank you for your question.There is no interaction between the 2 drugs but if you are concerned that the physical injection may trigger the condition then have a test injection of 1-2 units in the forearm.Kind Regards Dr Dinesh Maini Zenith Cosmetic Clinics 

Hi,
I recommend you follow up with a board certified dermatologist regarding initiating Botox while on Xolair for chronic urticaria. As you know, the latter is an interesting condition in that many things (pressure, cold, water, light, among many others) can be potential triggers. Medications are often the cause of chronic urticaria. That I know of, Botox has not been implicated as a possible trigger, but it is possible.  With that in mind, it is possible you could experience a flare if this is a potential etiology. It is also important your dermatologist screen you for possible disease associations with chronic urticaria. At the end of the day this is probably a conversation best had with your dermatologist to discuss the risks and benefits of restarting Botox. Hope this helps.
Kevin Cavanaugh, MD