Lips were overfilled and improperly placed. Tried to dissolve it with hyaluronidase but got an allergic reaction. Advice?

Hylauronidase has many advantages and should be considered in patients who are unhappy with their results or in acute cases of overfilling or occlusion. Its often better to reverse filler and restart then to deal with long term edema. Filler migration and permanence is a very common problem because there are many different types of HA fillers on the market and each is specified for a specific part of the face. Use of highly cohesive fillers on thin skin may cause swelling and nodularity. If patients have filler migration or nodules, we recommend a combination approach of filler reversal with enzymes Hylenex and Hyaluronidase in different strengths to dissolve the filler. We may also need to add Kenalog to the mix in order to reduce fibrous tissue. If the filler does not dissolve, it either means the filler is not HA material or we need more enzyme. The HA reversal can be combined with other lasers and skin treatments at the same time, and it usually (usually) does not affect adjacent tissue.

Best,
Dr. Karamanoukian
Realself100 Surgeon

Hylenex is recombinant human hyaluronidase and is what I always use. It shouldn't have an allergic reaction. It is very safe. It might take more than one treatment.

Hi sorry to hear of your problems. Wait for settling to go down over the next few weeks. Then revaluate. All lip fillers disappear with time, dissolving lip fillers might leave you with an uneven result. Hope this helps warm regards Dr Prashant Murugkar