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What is the Most Effective Cumulative Dose for Accutane?

redtape1Jun 1, 2012
I have read that the most effective cumulative dose for Accutane is between 120-150mg/kg. Does this only improve chances of Accutane efficacy if you go beyond the 150mg/kg cumulative dose (e.g. 160mg/kg, 180mg/kg, etc.)? Or is reaching the 150mg/kg about as effective as it's going to get?

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From board-certified doctors and trusted medical professionals
Dr. F. Victor Rueckl, MD (in memoriam)
Board Certified Dermatologist
Answered on Jun 5, 2012
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F. Victor Rueckl, MD (in memoriam)

This largely depends. Are you on medication for your mild depression and anxiety? What does that prescribing physician think? I've had patients over the years come in with mild depression and anxiety and a lot of it had to do with how they looked. So once we put them on Accutane and they started...

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Jeffrey C. Poole, MD - Account Suspended

Isotretinoin is not known to cause low blood pressure, and I have not encountered this as a problem in over 12 years of prescribing the medicine.  I would discuss with your primary physician about other causes for your blood pressure. Of note, Accutane, the original brand of...

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F. Victor Rueckl, MD (in memoriam)

There are many patients whom I put on a low dosage like this for long-term maintenance, but usually after they've already undergone a regular course. It's important to understand that the purpose of taking Accutane is to get a minimum mg of the medication into your system to combat your weight...

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