2 weeks post-op and I have itchiness and binder discomfort. What can I do to make it easier on me? I've tried Benadryl.

Our office provides our TT/lipo patients with an ADJUSTABLE compression garment manufactured by Clear Point.  The  patients like the support it provides to the back and to the abdomen.  The only complaint I have heard is related to the "itchiness" of the fabric which can be remedied by wearing a soft t-shirt under the garment which you state that you wear with your M compression garment.
Kenneth Hughes, MD, ABPS Board Certified Plastic Surgeon
Los Angeles, CA

Wearing an extra layer (the garment) can trap sweat and cause itching.  Try using some baby powder on the itchy areas prior to putting on your t-shirt and garment. 

Dear Generous3844,
based on your description, it sounds like you tried to resolve your problem by yourself. I understand your concern. However, without a proper assessment it would be difficult to determine what is wrong. It is best that you visit your plastic surgeon for further assessment. Only after thorough examination you can get proper recommendations and advice.
Daniel Barrett, MD
Certified, American Board of Plastic Surgery
Member, American Society of Plastic Surgery
Member, American Society of Aesthetic Plastic Surgery

If having itching has been consistent and not improved I recommend that you return to your surgeon for an evaluation.  It may be that the binder is too tight and that a different size or compression strength should be ordered.  Your surgeon will guide you through this process.

Hi and welcome to our forum!
A compression garment is worn after surgery to control swelling and prevent bleeding. It does not result in reshaping, but may prevent hematoma or seroma. Some surgeons recommend use for 4-6 weeks, some longer, some shorter. Some do not recommend compression at all. Every plastic surgeon has his / her unique protocol for postoperative care based upon a lifetime of experience with what has worked best in the past. 
The garment should be snug but not tight. If it binds, a larger size may be required. Allergy or hypersensitivity to garment material can be troubling. You have already tried insulating the skin from the garment with a cotton shirt and benadryl.
I recommend you speak with your surgeon regarding possible alternatives.
Best wishes...