Possible complications with MTHFR gene mutation?

Question

I recently found out I have the duplicate gene mutation MTHFR with 2 copies of the 1298 gene. I am scheduled for surgery in Feb 2025 and am hesitant to move forward with surgery. My Dr also told me I have LP(a)- not sure what it's role would play in surgery. I am very anxious about my procedure as I recently had a breast biopsy done and had complications from that; found I have PASH and also developed a hematoma the size of a baseball. Can any of this hinder recovery for plastic surgeries?

Emily C. Wirtz, MD · Answer

Thanks for your question THolland, any time a patient has a finding that may impact bleeding risk, I recommend consulting with a hematologist prior to your surgery. This specialist is trained in different types of bleeding and clotting disorders and will be able to give you the best idea of your risks with elective surgery, as well as make recommendations about how to mitigate those risks.Hematoma after breast biopsy is not uncommon, but can raise concern about bleeding risk for future procedures.In your case, MTHFR mutation may actually increase your risk of having blood clots after surgery. I highly recommend you discuss this with both your surgeon and a hematologist prior to your surgery. Best of luck with your journey!- Emily Wirtz, MD

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Possible complications with MTHFR gene mutation?

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