Hi, i had juvederm injected into my tear troughs over 4 years ago. On one side only, there is persistent redness and a swollen lump. The lump is in the same place that the filler initially lumped when first done. Some days it swells so much my eye doesn't feel fully open. The swelling is soft to touch and causes dark shadows. Water consumption, anount of sleep have no effect. Please help!
Answer: Long term filler Although unusual, we have found (and I have seen myself) patients in whom the HA filler seems to last for many years in this area. Often you do well for a couple of years, and then it can start to swell and will often look blue under the skin. Injections of hyaluronidase will dissolve this, so we can assume that it is most likely persistent filler. It may take more than one injection to get rid of it completely. This has been seen with both Juvederm and Restylane.
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Answer: Long term filler Although unusual, we have found (and I have seen myself) patients in whom the HA filler seems to last for many years in this area. Often you do well for a couple of years, and then it can start to swell and will often look blue under the skin. Injections of hyaluronidase will dissolve this, so we can assume that it is most likely persistent filler. It may take more than one injection to get rid of it completely. This has been seen with both Juvederm and Restylane.
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February 22, 2017
Answer: Dissolve with hylauronidase and also see GP It's unlikely that this swelling is related to your previous filler
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February 22, 2017
Answer: Dissolve with hylauronidase and also see GP It's unlikely that this swelling is related to your previous filler
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Answer: Swelling Would Not Be Related to Filler after 4 Years Thank you for your question. I do not believe this is due to your previous filler. Your Juvederm filler would have dissolved a long time ago. The lump you are feeling is likely something else as Juvederm would not remain in your body for 4 years. Any swelling from your filler would have happened within the first week after injection as it is not possible for this to occur 4 years later. I recommend having a consultation with you primary physician to determine the cause of the swelling and lump you’re experiencing. Best of Luck!
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Answer: Swelling Would Not Be Related to Filler after 4 Years Thank you for your question. I do not believe this is due to your previous filler. Your Juvederm filler would have dissolved a long time ago. The lump you are feeling is likely something else as Juvederm would not remain in your body for 4 years. Any swelling from your filler would have happened within the first week after injection as it is not possible for this to occur 4 years later. I recommend having a consultation with you primary physician to determine the cause of the swelling and lump you’re experiencing. Best of Luck!
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February 21, 2017
Answer: Filler causing swelling years later If there is suspicion that there is any degree of persistent filler after a few years I would first attempt to dissolve it, which may take more than one injection, to see if that improves the issue. I would see your injecting physician in order to properly evaluate the area.
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February 21, 2017
Answer: Filler causing swelling years later If there is suspicion that there is any degree of persistent filler after a few years I would first attempt to dissolve it, which may take more than one injection, to see if that improves the issue. I would see your injecting physician in order to properly evaluate the area.
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February 21, 2017
Answer: What is the cause of swelling at site of Juvederm injection 4 years later? In general, HA derivatives like Juvederm are well tolerated & safe. However, there have now been several cases of delayed adverse effects. I did a little research and found the article Foreign Body Reaction to Injectable Hyaluronic Acid: Late Granuloma Formation in the Annals of Dermatology (2015 Apr; 27(2): 224–225. Published online 2015 Mar 24). They propose low grade bacterial infection on a foreign body, such as Juvederm, may result in a delayed granulom formation: "There are several theories regarding the cause of this reaction. First, impurities may lead to hypersensitivity responses. Second, disintegration of the cross-linked product may provoke an inflammatory response. Third, recent studies propose that concomitant bacterial inoculation during the filler injection may cause late granuloma formation. In most cases, bacterial infections become clinically apparent within several days after HA injection. However, biofilms consisting of bacteria, their nutrients, and wastes on the surface of foreign bodies enable persistent minimal infection with little host response, and they become symptomatic months or even years after. Foreign body reactions to biofilm rather than to pathogenic bacteria may produce delayed granuloma formation." Their case is similiar to yours and I recommend you see your family physician or internist. A biopsy of the area will be required for diagnosis.
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February 21, 2017
Answer: What is the cause of swelling at site of Juvederm injection 4 years later? In general, HA derivatives like Juvederm are well tolerated & safe. However, there have now been several cases of delayed adverse effects. I did a little research and found the article Foreign Body Reaction to Injectable Hyaluronic Acid: Late Granuloma Formation in the Annals of Dermatology (2015 Apr; 27(2): 224–225. Published online 2015 Mar 24). They propose low grade bacterial infection on a foreign body, such as Juvederm, may result in a delayed granulom formation: "There are several theories regarding the cause of this reaction. First, impurities may lead to hypersensitivity responses. Second, disintegration of the cross-linked product may provoke an inflammatory response. Third, recent studies propose that concomitant bacterial inoculation during the filler injection may cause late granuloma formation. In most cases, bacterial infections become clinically apparent within several days after HA injection. However, biofilms consisting of bacteria, their nutrients, and wastes on the surface of foreign bodies enable persistent minimal infection with little host response, and they become symptomatic months or even years after. Foreign body reactions to biofilm rather than to pathogenic bacteria may produce delayed granuloma formation." Their case is similiar to yours and I recommend you see your family physician or internist. A biopsy of the area will be required for diagnosis.
Helpful 2 people found this helpful
