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While the coolsculpting technology certainly works, you have to be able to fit an applicator to the area in question. Knees and calves are hard to fit - so, it might not be possible to treat you. Best to go have a consult with a surgeon that offers Coolsculpting, and see if the applicators are compatible with your anatomic shape.
CoolSculpting has FDA approval for fat reduction since 2010. CoolSculpting freezes the fat cells. Fat cells are more susceptible to damage by freezing than the other cells, (nerve, vessel, bone, etc.), around them. The fat cells die via a process called apoptosis, (programmed cell death). The number of fat cells are therefore reduced. This happens over a period of time, so the body is not overwhelmed with dead fat cells. The body will take these cells up, process them and excrete them, just as any other cell. The remnants are filtered through the liver, and then excreted eventually via stool. Knees can be a challenge with any modality. CoolSculpting has a specific applicator that has been used in this area with good results. Calves may be more difficult. See an experienced CoolSculpting practice, they will determine if you are a candidate. Would also consider seeing a Board Certified Plastic Surgeon, who can give advice on both CoolSculpting and Liposuction.
Unfortunately, CoolSculpting cannot be done on these areas with the applicators currently available. The treatment area needs to have pinchable and pliable fat in order to fit into the applicator properly.
Coolsculpting is FDA approved for abdomen, back, inner thighs and outer thighs. It is not approved for knees and calves. I have seen some photos from other providers that do not look pleasing if these areas are treated.
CoolSculpting is not FDA approved for fat reduction from the knees or calves. It is possible to sometimes treat a non-FDA approved area, but you would need to be examined to determine if that might be possible.