Thank you for sharing your questions and photos. Neurotoxin to the depressor anguli oris (DAO) will help relax this muscle and lessen the downward pull of the corners of your mouth. Typically, 2-4 units are injected per side depending on how strong the individual’s muscles are. Additionally, neurotoxin can also be injected in the perioral oral area to provide a “lip lift” effect. If injections are done more laterally in the perioral area then it could also help with widening the appearance of the corners of your mouth. Please note that the main risks of neurotoxin injections include but are not limited to, pain, swelling at the injection site, bruising, headache, and asymmetrical results. Notably, this treatment is not permanent and can last between 3-6 months. It is important to go to an experienced injector to optimize safety and to achieve your desired outcome. Best of luck! Kian Karimi MD, FACS