A potential side effect of any weight loss is loss of volume (fat *and* muscle) everywhere, including the face. Due to the decreased collagen production and regeneration later in life, this loss of volume can often be accompanied by sagging or crepey skin- but this can also be caused by *rapid* weight loss, as is the case with "Ozempic face". In our office, we take a holistic approach to using semaglutide (ozempic, wegovy) and tirzepatide (mounjaro, zepbound) so as to mitigate as many of the deterring side effects as possible. Dosing to maintain an average 1-3lbs of weight loss per week is particularly helpful. Additionally, treatments such as Sculptra, PRP, and RF-Microneedling are important steps in maintaining facial volume and improving skin health. For the body, EmSculpt NEO is a great way to ensure muscle building during the program, as well as Conjugated Linoleic Acid as a take-home supplement. When used appropriately and under the right guidance, these medications are a wonderful option for weight loss for many people. Best of luck! Genie Alexander, RN BSN for Dr. Anna Petropoulos, MD FRCS at Center for Classic Beauty, Danvers & Boston, MA.