What are the side effects of Jeuveau?

Jeuveau is the newest FDA-approved member of the family of neuromodulators with Botox being the most widely used and well-know member. Both medications are very similar in terms of action and also the possible side effects and there is really not much difference. For all these medications, most side effects are mild, temporary and self-limiting and may include issues at the sites of injection (bruising, redness), issues related to over-relaxation of the muscles (droopy eyelids) and at times headache. Side effects related to spread of injections beyond the treated ares and systemic reactions are also possible although extremely rare. I hope it helps and good luck!

Jeuveau is a type A neuromodulator, just like Botox.  It has the same molecular weight and has the exact same side effect profile.  Potential side effects that we rarely see are: bruising, eyelid ptosis (droop) and eyebrow ptosis (droop), which are all temporary.  While eyelid ptosis is the worst of these, it is not dangerous but does look bad.  It has a 1% risk among all injectors but in our office we see it less than 1 per 1000 treatments.

Side effects of Jeuveau may be the same as other neurotoxins - asymmetry, need for a dose adjustment, failure to achieve a desired result, bruising, or temporary upper eyelid droopiness (ptosis). Hope this helps! Dr Joseph

The precautions are the same as all the other neuromodulators.  Make sure your injector is an expert and is up to date on current use of the products and is board certified.  You might have some redness and a little pain on injection, possibly some bleeding and/or bruising, and if improperly placed, some asymmetry or drooping of some muscle groups.  Otherwise, we love Jeuveau and are hoping it might last longer than the other competitors, but only time will tell!  Best of luck!

Hello from New York City! Thanks for your question.Jeuveau and Botox are both 900 kDa botulinum type A neuromodulators. Botox was developed 30 years ago and Jeuveau was FDA-approved on February 1st. It was developed for and is approved for cosmetic uses only, unlike Botox. It is a premium product that is manufactured in a factory built specifically for this purpose in South Korea with state-of-the-art technology and hardware. The quality control standards are high and it’s Hi-Pure technology utilizes two passes through chromatography columns, resulting in a preparation with fewer impurities and making it more expensive to manufacture than Botox. In the vial of each are also albumin and saline. In studies of more than 2100 patients treated with Jeuveau and Botox, the side effects were exactly the same: there were a small number of patients with discomfort or bruising, and about 1% across all studies performed thus far had temporary drooping of the eyelid (treatable with eye drops). When the same number of units are injected in greater concentration, ie., less saline is used to dilute the powder in the vial, there is less diffusion and even this side effect should be extraordinarily rare. In general, both neuromodulators were equally safe and free of any serious or long term adverse events.I hope this answers your question!Sheryl Clark MD FAAD

Jeuveau is a neuromodulator which is similar to Botox.  The side effects are also similar.  Some include redness at the injection site and bruising.  The product is considered in full effect after two weeks and the results will fade gradually over 3 to 4 months.  See an expert injector near you to learn more.

Thank you for your question. I understand your concern. Jeuveau is a purified protein used to address wrinkles associated with facial expression. When injected into the skin Jeuveau will relax the muscles and smoothen out the overlying wrinkles. The most common areas of treatment are in the upper face. These include the horizontal lines seen on the upper forehead when one raises the brows, the vertical lines seen between the brows when one frowns (frown lines), and the crow's feet seen around the eyes when one smiles.
The safety record of Jeuveau is very similar to Botox. Jeuveau is amongst the safest treatments for treating facial wrinkles.
While Jeuveau is one of the safest treatments offered, there are some situations where it is not appropriate. These include anyone who has an allergy to any of the inactive ingredients or who has had an allergic reaction to any botulinum product including Jeuveau, Botox, Dysport, Xeomin, or Myobloc. The safety and efficacy of Jeuveau has not been established in women who are pregnant, trying to become pregnant, or breast feeding. Therefore, women in these categories are advised to wait until breast feeding is completed prior to having a Jeuveau treatment. Jeuveau should not be placed in the skin on the site of an infection. Those who are taking an aminoglycoside antibiotic, an anesthetic, D-penicillamine, antimalarials, or immunosuppressants should not be treated, nor should those who have undergone chemotherapy within the previous six months. It is important to avoid blood thinners before and after a treatment. These include both prescription and non-prescription medications such as warfarin (coumadin), aspirin, ibuprofen, alcohol, fish oil, vitamin E, and ginko biloba. Those with conditions that affect muscles and nerves such as amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease), myasthenia gravis, or Lambert-Eaton syndrome should not undergo Jeuveau treatments.With any injection, there are risks such as pain, bleeding, bruising, redness, swelling, tenderness, and infection. We take special precautions to minimize these risks such as using a painless technique. We also treat bruises with a laser as early as the next day. Bruises usually resolve within two weeks if untreated. After a laser treatment bruises usually resolve in 1-3 days, but may still take two weeks for full resolution. In addition to these risks, with Jeuveau there is also a risk that the product spreads or diffuses to nearby structures. Spread to nearby muscles can lead to side effects such as the temporary appearance of droopy eyelids or a temporary asymmetric smile.

After a Jeuveau treatment, I recommend that my patients avoid heat exposure, alcohol consumption, and strenuous exercise for 24 hours and not lie down flat for four hours. This is because all of these activities may possibly lead to the movement of the product and consequent side effects such as droopy eyelids. Although there have been no definitive studies shown that these actually occur and some physicians do not provide such aftercare instructions, in the absence of data I err on the side of caution and recommend that my patients avoid such activities.

Please consult with a doctor for specific recommendations. Good luck!

Although Jeuveau is another form of botulinum toxin type A (prabotulinumtoxin), it is almost identical to Botox in every way, including potential side effects. Jeuveau will be reconstituted just like Botox in the doctor's office, the same number of units will be injected as Botox, and it has the same clinical effect as Botox. Both the doctor and patient will not be able to tell them apart. However, in extensive clinical trials, Jeuveau did appear to last longer than Botox. It should be the first serious competitor to Botox because of its expected aggressive pricing.