Thank you for your question regarding the safety of waxing while taking isotretinoin (Accutane). Isotretinoin is known to make the skin more sensitive and fragile, which can increase the risk of skin injuries during procedures like waxing. Here are some key considerations: Increased Skin Sensitivity: Isotretinoin reduces the amount of oil produced by the skin, leading to increased dryness and sensitivity. This can make the skin more prone to tearing or irritation from waxing. Recommendation: Generally, it is advised to avoid waxing while on isotretinoin and for at least six months after completing the treatment. This is to prevent potential skin damage such as tearing, irritation, or scarring. Alternative Hair Removal Methods: Consider other hair removal methods such as shaving or using a depilatory cream that is suitable for sensitive skin. Always conduct a patch test first to ensure there is no adverse reaction. Consultation: It is best to consult with your dermatologist before proceeding with any hair removal method to ensure it is safe for your specific circumstances. Your dermatologist can provide personalized advice based on your skin type and treatment plan. Best regards,