Can Roaccutane and tazarotene result in a nose-thinning effect?

It's important to understand that the primary purpose of medications like Roaccutane (isotretinoin) and Tazarotene is to treat severe acne and other skin conditions, not to alter the physical structure of the nose. Roaccutane can indeed reduce the size of sebaceous glands and the amount of oil they produce, which can potentially minimize the appearance of pores and make the skin, including the nose, appear smoother and less oily. However, this effect is temporary and will revert once the medication is discontinued. It's also worth noting that this doesn't actually change the physical structure or "thin" the nose in any significant way.As for Tazarotene, it is a retinoid like tretinoin, and it primarily works by promoting skin cell turnover. While it can help improve the texture and appearance of the skin, it does not have a notable effect on the size or shape of the nose.Spironolactone, on the other hand, is primarily used to treat hormonal acne and has no known effects on the size or shape of the nose.While some patients may perceive subtle changes in the appearance of their nose while on these medications, it's crucial to understand that they are not designed or indicated for physical alterations to facial features. Any significant changes to the shape or size of the nose would require surgical intervention.