Before a bottle is mixed with the solution, should you be able to see powder in 100 unit bottle? (Photo)

You will not see any "powder", although you will see a small film to the bottom of the bottle. When training this is one of the first things you learn. Please ensure you are a trained injector before experimenting with Botox. 

There is no powder in an unreconstituted vial of Botox. There is typically just a slight haze on the bottom of the vial that represents the product. All trained injectors are aware of this. If you're not 100% confident and well trained in what you are doing please do not inject whatever you are holding in the photo into your face or the face of another. Stephen Weber MD, FACSDenver Facial Plastic Surgeon

Thank you for your question. No powder will be visible, however you should see a slight film at the bottom.

If this is a bottle of botox then this is the normal appearance prior to reconstituting the botulinum toxin.  Allergan's botulinum toxin has the ring of white powder material at the stuck to the bottom of the bottle.  Xeomin is a powder that can be shaken around the bottle prior to reconstitution.

I'm a bit confused about why you are asking this question, and why you have photos of you holding a vial.... If you want to verify that you have a real vial (please tell me you are
in a medical office and you did NOT purchase this online), then you can
simply call Allergan, read them the lot numbers on the vial, and have
them assist you. If you did buy this online, please do not use this!! It
is dangerous and a medication and you need to be experienced to do
Botox injections. For anyone else who is just curious though, when you pull a vial of Botox out of the box it will have what almost looks like a frost coating the bottom of the vial. It's not a large amount of powder and since Botox is delivered to you in a frozen state it makes the powder adhere to the bottle itself. When the liquid is put in, it's pulled off the vial and becomes a part of the liquid which you then use to inject. "This answer has been solicited without seeing this patient and
cannot be held as true medical advice, but only opinion. Seek in-person
treatment with a trained medical professional for appropriate care."